Fig. 2

Hematoxylin and eosin staining of the lung biopsy demonstrate diffuse proliferation of large cells at lower power (10×, A). Immunohistochemistry staining (10×, B, C) of the lung biopsy shows positive for CD20 and Ki-67.Hematoxylin and eosin staining of the bone marrow demonstrate active hematopoiesis with an increased granulocyte ratio and decreased erythroid ratio (10X, D)