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TABLE 2 Outcomes of induction treatment

From: Induction hepatic arterial infusion chemotherapy followed by surgery for hepatocellular carcinoma with massive portal vein tumor thrombosis: a case series of 20 patients

Case

Number of

HAIC courses

Total dose

of RT (Gy)

Treatment

response

Adverse events

(grade 2 or more)

Surgical

indication

Reason for being

unresectable

1

1

40

PR

Thrombocytopenia

Resectable

2

8

50

PR

Thrombocytopenia

Resectable

3

1

PD

None

Unresectable

Progression

4

2

50

SD

Thrombocytopenia

Resectable

5

1

50

PD

Thrombocytopenia

Unresectable

Progression

6

1

50

SD

Leukopenia, anemia

Unresectable

Decline in liver function

7

2

50

PR

Thrombocytopenia

Unresectable

Decline in liver function

8

1

PD

Thrombocytopenia

Unresectable

Progression

9

2

PD

Cerebral infarction

Unresectable

Progression

10

2

PR

Anemia, thrombocytopenia

Resectable

11

1

PD

None

Unresectable

Progression

12

2

50

SD

Neutropenia, anemia,

thrombocytopenia

Resectable

13

1

PD

None

Unresectable

Progression

14

2

39

SD

Neutropenia, anemia,

thrombocytopenia

Resectable

15

1

50

SD

Anemia, thrombocytopenia

Resectable

16

1

50

SD

Hemobilia

Unresectable

Decline in liver function

17

2

50

PR

Neutropenia, anemia,

thrombocytopenia

Resectable

18

1

45

PD

None

Unresectable

Progression

19

1

50

PR

Anemia, thrombocytopenia

Resectable

20

1

50

PR

Thrombocytopenia

Resectable

  1. HAIC, hepatic arterial infusion chemotherapy; RT, radiotherapy; PR, partial response; SD, stable disease; PD, progressive disease